Is Apathy an Early Sign of Dementia?

“Older adults who aren’t interested or enthusiastic about their usual activities may have a higher risk of developing dementia, new research suggests.” – WebMD 

Oct 14, 2020

American Academy of Neurology |

MINNEAPOLIS – Older adults with severe apathy, or lack of interest in usual activities, may have a greater chance of developing dementia than people with few symptoms of apathy, according to a study published in the October 14, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.

...article continued below
- Advertisement -

Study author Meredith Bock, M.D., of the University of California, San Francisco said:

“Apathy can be very distressing for family members, when people no longer want to get together with family or friends or don’t seem interested in what they used to enjoy.

“More research is needed, but it’s possible that these are signs that people may be at risk for Alzheimer’s disease and could benefit from early interventions and efforts to reduce other risk factors.”

The study involved 2,018 adults with an average age of 74. None had dementia.

At the start of the study, researchers measured apathy using a survey with questions such as “In the past four weeks, how often have you been interested in leaving your home and going out?” and “In the past 4 weeks, how often have you been interested in doing your usual activities?”

...article continued below
- Advertisement -

Participants were then divided into three groups: those with low, moderate and severe apathy. After nine years, researchers determined who had dementia by looking at medication use, hospital records and results on cognitive tests.

By the end of the study, 381 participants, or almost 19%, developed dementia. In the low apathy group, 111 out of 768 people, or 14%, developed dementia, compared to 143 out of 742 people, or 19%, in the moderate apathy group.

In the severe apathy group, 127 out of 508 people, or 25%, developed dementia. After adjusting for age, education, cardiovascular risk factors and other factors that could affect dementia risk, they found that people with severe apathy were 80% more likely to develop dementia than people with low apathy.

Greater apathy was also associated with worse cognitive score at the beginning of the study.

“While depression has been studied more extensively as a predictor of dementia, our study adds to the research showing that apathy also deserves attention as an independent predictor of the disease,” Bock said. “In fact, we believe that apathy may be a very early sign of dementia and it can be evaluated with a brief questionnaire.”

A limitation of the study is that an algorithm was used to diagnose dementia, which may not be as sensitive as an in-depth evaluation by a doctor.

The study was supported by the National Institute on Aging.

The American Academy of Neurology is the world’s largest association of neurologists and neuroscience professionals, with 36,000 members. The AAN is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, concussion, Parkinson’s disease and epilepsy.

CORRECTION: Our original headline incorrectly stated that the study in question identified apathy as a cause of Alzheimer’s. The study finds that apathy is an indicator of Alzheimer’s, not a cause. 


Age-Related Dementia is REVERSIBLE

The Most Common Early Signs Of Dementia”

ALSO ON HEADLINE HEALTH TODAY: Robert Redford Family: “Our Grief Is Enormous” | Beach Volleyball Champ Shamed After Equating Masks, Slavery | Common Item Kills 99.9% Of Coronavirus On Contact

- Advertisement -


UK Woman Insists Vaccine Turned Her Into An ‘Alien’

THE NEW YORK POST – A UK woman said she felt like a creature in the sci-fi horror flick “Alien” when she broke out...

Masks “Do Not Impact The Spread Of The Virus”: FL Official

Florida Education Commissioner Richard Corcoran is telling school districts that currently have mask mandates to make what national health leaders consider protection, voluntary when the school year begins come fall.

Symptoms Of A Blood Clot And How To Prevent Them

Most people probably don’t think about blood clots on a regular basis. But with reports of a small number of people developing blood clots after they received either the Johnson & Johnson or the AstraZeneca COVID-19 vaccine, many people are now wondering what the warning signs are.

Evangelicals’ Anti-Vaccine Sentiment Explained

(CNN)At Pastor Tony Spell's Sunday sermon this week, he preached a different kind of message than usual to his congregants: Don't trust Covid-19 vaccines. "I'll...

WHO Calls For Pause On Sale Of Live Animals In Markets

FOOD SAFETY NEWS – The World Health Organization (WHO) and other agencies are calling on countries to suspend the sale of certain live caught...

Toddlers Lives Matter? Man Charged In Death Of Boy, 2, Who Peed On Couch

A Florida man allegedly fatally beat his girlfriend’s two-year-old son after the child urinated on the couch, a report said.

Covid Itself – Not The Vaccine – Is Causing These Blood Clots

Far more COVID patients suffer from blood clots after leaving the hospital than previously realized, according to recent research published in the journal Blood.

FDA Approves Mail-Order Abortions

Women seeking an abortion pill will not be required to visit a doctor's office or clinic during the COVID-19 pandemic, U.S. health officials said Tuesday in the latest reversal in an ongoing legal battle over the medication.

Bill Gates, Vaccine Monster

THE NEW REPUBLIC – On February 11, 2020, public health and infectious disease experts gathered by the hundreds at the World Health Organization’s Geneva...

Muslim Circumcision Festival Proceeds Despite Virus

Muslims from the southwestern corner of Bulgaria flocked to the sleepy mountain village of Ribnovo for a four-day festival of feasting, music and mass circumcisions.
- Advertisement -