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Frozen Embryos Linked To 74% Greater Risk of Dangerous Disorder

SCITECH DAILY – Compared to naturally conceived pregnancies, pregnancies conceived with assisted reproductive technology using frozen embryos, may have a 74% higher risk of developing a hypertensive disorder.

In comparison, the risk of hypertensive disorders in pregnancies from fresh embryo transfer was similar to naturally conceived pregnancies.

High blood pressure during pregnancy may be a sign of preeclampsia, a serious pregnancy complication that may be life-threatening to both the mother and the fetus.

According to new research published on September 26 in Hypertension, in vitro fertilization (IVF) using frozen embryos may be associated with a 74% higher risk of hypertensive disorders in pregnancy. Hypertension is a journal of the American Heart Association.

In comparison, the study found that pregnancies from fresh embryo transfers – transferring the fertilized egg immediately after in vitro fertilization (IVF) instead of a frozen, fertilized egg – and pregnancy from natural conception shared a similar risk of developing a hypertensive disorder.

“Frozen embryo transfers are now increasingly common all over the world … some doctors have begun skipping fresh embryo transfer to routinely freeze all embryos in their clinical practice.”

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High blood pressure during pregnancy often signals preeclampsia, a pregnancy complication including persistent high blood pressure that can endanger the health and life of both the mother and fetus.

According to the American Heart Association, around 1 out of every 25 pregnancies in the United States results in preeclampsia.

Preeclampsia is high blood pressure and signs of kidney or liver damage that occur in women after the 20th week of pregnancy. It occurs in around 3% to 7% of all pregnancies.

While rare, preeclampsia can also occur in a woman after delivering her baby, most often within 48 hours. This is known as postpartum preeclampsia.

While the exact cause of preeclampsia is unknown, the condition is thought to start in the placenta …

“Frozen embryo transfer is known to be associated with a higher risk of hypertensive disorders in pregnancy than both natural conception and fresh embryo transfer.”

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