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In the hunt for a male contraceptive, scientists look to stop sperm in their tracks

NPR – Condoms have been used to prevent pregnancy since the Middle Ages, with the rubber version arriving in the industrial mid-1800s. Over the years, they’ve become more effective and comfortable to use.

But it was the invention of birth control pills, followed by IUDs in the 1960s, that created a seismic shift in humans’ ability to control reproduction.

A growing range of pills, patches and implants became available to women. And yet, a stretchy sheath that covers the penis remains the only medically approved form of contraception for men, short of vasectomy.

But now, researchers are looking into both hormonal and non-hormonal contraceptives for sperm bearers. The hope is that couples will begin to treat contraception more as a shared responsibility.

Listen to Short Wave. This story is adapted from an episode of Short Wave, Beyond Condoms. Explore more of NPR’s daily science podcast.

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“We would like to create a menu of options for men similar to what women have available to them,” says Stephanie Page, a researcher and endocrinologist at the University of Washington.

Hormonal methods get renewed research

Dr. Page’s lab is conducting a clinical trial along with researchers at 15 other sites across the globe, testing out a topical gel that a man applies to his shoulders every day.

The gel contains synthetic hormones – a combination of testosterone and progestin – that signal the brain to lower testosterone levels in the body.

And since testosterone is necessary for sperm to reach maturation, the testes then produce fewer and fewer sperm …

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