UNIVERSITY OF WASHINGTON MEDICINE – A CDC report shows that only 23% of pregnant women in the United States had been vaccinated by the end of July. The percentage is even lower among Black and Latina women.
1. Pregnant women’s vaccine reactions are pretty similar to everyone else’s … not much.
A survey of more than 17,000 pregnant and lactating individuals who received the COVID-19 vaccine showed that the individuals did not experience symptoms any more severe than their non-pregnant counterparts.
The UW Medicine study, published today in JAMA Network Open, showed “there were not any increased reactions in pregnant individuals beyond what is expected from a vaccine” said Dr. Linda Eckert, a professor of obstetrics and gynecology at the University of Washington School of Medicine and the study’s senior author.
“Pregnant people do well with the vaccine,” added lead author Dr. Alisa Kachikis.
The findings come a week after the Centers for Diseases Control and Prevention formally recommended that all pregnant women get vaccinated against the virus.
2. New and expecting are reassured after getting vaccinated.
“We hope that this data will be another reassuring piece of information … about why pregnant individuals need to get vaccinated against COVID-19,” Dr. Eckert said.
“Not only is the vaccine safe, our research shows just how well the vaccine is tolerated in pregnant individuals—which is a common fear I hear from my patients. In contrast, we are continuing to learn more and more about just how dangerous COVID-19 infections are in pregnancy.”
In January 2021, Kachikis set up an online cohort study of women: those who were pregnant or lactating and those who were neither pregnant nor lactating. The women were invited to describe their reactions after receiving at least one dose of a COVID-19 vaccine. By March, 17,525 individuals had responded.
There are currently 20,000 women enrolled in the study and new respondents continue to post their experiences, Kachikis added.
The researchers hope to expand the study to other socioeconomic groups and to women not so closely tied to heathcare, as this group was, Eckert said.
3. Vaccinated moms provide encouragement for further studies to help other women.
“I think this gives a level of evidence to advocate for Phase 3 trials (for pregnant individuals) in the future,” Eckert said.
Aside from the CDC vsafe registery, this is the largest U.S. study of this issue. Canada has created a registry based on Kachikis’ model.
This research was supported by the National Center For Advancing Translational Sciences (UL1 TR002319) and by the National Insitute of Child Health and Human Development Women’s Reproductive Health Research Award (2 K12HD001264-21) for the purposes of design and conduct of the study; collection, management, analysis, and interpretation of the data. T
he UW Institute of Translational Health Science provided administrative Research Electronic Data Capture support for this project and was supported by grants UL1 TR002319, KL2 TR002317, and TL1 TR002318 from NCATS. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.