World’s First Gene-Edited Babies May Have Shorter Lives

Image: twitter.com/crisprtwins

Nature Medicine – In 2018, Chinese scientist He Jiankui claimed he used the CRISPR/Cas9 tool to disable the CCR5 gene in the embryos of twin girls, Lulu and Nana.

The twins, He theorized, would be protected from HIV.

Now, research published in the journal Nature Medicine suggests He might have shortened the girls’ life expectancies.

Now an analysis of the DNA and death records of more than 400,000 volunteers in the UK Biobank — a large British gene database.

When researchers matched the DNA with death records, they discovered that people with two non-working CCR5 genes passed away 20 percent faster than the rest of the sample population.

That may be because people with a CCR5 mutation appear to be more susceptible to illnesses like West Nile virus or influenza … Read more. 

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