UPDATE: Since we first reported in late 2017 on the Trump EPA’s innovative plan for ending mosquito borne diseases, scientists have developed another avenue to killing off the world’s deadliest animal …
How to stop mosquitoes from reproducing
Dismantling one protein, researchers caused mosquitoes to lay damaged eggs that couldn’t grow embryos. (Jun Isoe)
STAT Morning Rounds, Jan 9, 2019 –
Experts are investigating a number of ways to make mosquitoes unable to reproduce or spread disease, including infecting them with a type of bacteria or editing their genes.
Now, researchers have another target: a newly discovered protein involved in making eggs dubbed eggshell organizing factor 1, or EOF1.
When researchers hampered the activity of the protein in females, the eggs they laid were damaged and the embryos in those eggs died.
What’s more, the protein is only found in mosquitoes, so any potential efforts to dismantle the protein in wild mosquito populations shouldn’t affect other animals.
RESEARCH ARTICLE on mosquito-specific eggshell protein
PLOS Biology – Mosquito-borne diseases are responsible for several million human deaths annually around the world.
One approach to controlling mosquito populations is to disrupt molecular processes or antagonize novel metabolic targets required for the production of viable eggs.
To this end, we focused our efforts on identifying proteins required for completion of embryonic development that are mosquito selective and represent potential targets for vector control …
The results provide new insights, to our knowledge, into mosquito egg maturation and eggshell synthesis and could lead to key advances in the field of mosquito vector control. Read more.
ORIGINAL STORY – Headline Health, November 9, 2017
Bacteria + Sex = Death for wild kingdom’s #1 killer
Their offspring will not survive in these 20 states …
The 5 Deadliest Animals in the World
(#1 is now in big trouble in 20 states)
Add them all together and these four killers take 86,000 lives per year. This leaves the #1 most dangerous member of the animal kingdom, a virtual killing machine …
According to the World Health Organization, about 725,000 people are killed every year by diseases carried by just one member of the animal kingdom.
This killer carries malaria, dengue fever, yellow fever, and encephalitis; malaria alone affects 200 million people worldwide, of which an estimated 600,000 die.
Unlike many other dangerous creatures, they can be found in nearly every part of the world at various times of year, and at peak breeding season they outnumber every other animal except ants and termites.
This killer is the tiny mosquito. The sheer number of mosquitoes adds to the risk they pose to humans.
The Trump administration has just approved a revolutionary approach to ending mosquito-borne diseases. The method is approved for use in 20 states.
Now that it has approval from the Environmental Protection Agency, this potent new weapon could finally solve the deadly pandemic of disease-carrying mosquitos … details below.
EPA Registers the Wolbachia ZAP Strain in Live Male Asian Tiger Mosquitoes
WASHINGTON – On November 3, 2017, EPA registered a new mosquito biopesticide – ZAP Males® – that can reduce local populations of the type of mosquito (Aedes albopictus, or Asian Tiger Mosquitoes) that can spread numerous diseases of significant human health concern, including the Zika virus.
ZAP Males® are live male mosquitoes that are infected with the ZAP strain, a particular strain of the Wolbachia bacterium. Infected males mate with females, which then produce offspring that do not survive. (Male mosquitoes do not bite.) With continued releases of the ZAP Males®, local Aedes albopictus populations decrease. Wolbachia are naturally occurring bacteria commonly found in most insect species.
This time-limited registration allows MosquitoMate, Inc. to sell the Wolbachia-infected male mosquitoes for five years in the District of Columbia and the following states: California, Connecticut, Delaware, Illinois, Indiana, Kentucky, Massachusetts, Maine, Maryland, Missouri, New Hampshire, New Jersey, Nevada, New York, Ohio, Pennsylvania, Rhode Island, Tennessee, Vermont, and West Virginia.
Before the ZAP Males® can be used in each of those jurisdictions, it must be registered in the state or district.
When the five-year time limit ends, the registration will expire unless the registrant requests further action from EPA.
EPA’s risk assessments, along with the pesticide labeling, EPA’s response to public comments on the Notice of Receipt, and the proposed registration decision, can be found on www.regulations.gov under docket number EPA-HQ-OPP-2016-0205. Source: epa.gov
[IMAGES: Croc, Pexels.com; fly, Oregon State University; dog, Matt Reinbold, CC; Ben Fruen, CC; snake, Herman Pijpers]
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